E-Cadherin-EP6

E-Cadherin is a transmembrane glycoprotein, plays an important role in epithelial cell adhesion. A decreased expression of E-Cadherin is associated with metastatic potential and poor prognosis in breast cancer and esophagus cancer. In combination with p120 Catenin or Cytokeratin, it is useful for the differentiation between ductal (E-Cadherin positive) and lobular (E-Cadherin negative) breast carcinomas. It may also help in diagnosis of mesothelioma.

• Source
  Rabbit Monocclonal
• Clone
  EP6
• Class
  IVD
• Isotype
  Rabbit IgG
• Tested Reactivity
  Human, FFPE
• Localization
  Membranous
• Positive Control
  Colon Ca, Breast ductal Ca

• Catalog
  Pack Size
• PR039-3ml
  3 ml(RTU)
• PR039-6ml
  6 ml(RTU)
• PR039-0.1 ml
  0.1 ml(Conc.)
• PR039-0.5ml
  0.5 ml(Conc.)
• HAR039-3ml
  3 ml(RTU)
• HAR039-6ml
  6 ml(RTU)
• CR039 - 1ml
  1ml ( Conc. )

1. Coalition of E-cadherin and vascular endothelial growth factor expression in predicting malignant transformation in common oral potentially malignant disorders
   https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917540/