Human placental lactogen (also called CSH1 or HPL), is a member of the human growth hormone(hGH)/human placental lactogen gene family. It is important in the regulation of maternal and fetal metabolis, as well as the growth and development of the fetus. HPL is a secreted by the syncytiotrophoblast during pregnancy. Antibody to HPL reacts with syncytiotrophoblastic cells in choriocarcinoma and intermediate trophoblasts in trophoblastic tumors. It is a useful marker for tumors with trophoblast differentiation.
Human placental lactogen (also called CSH1 or HPL), is a member of the human growth hormone(hGH)/human placental lactogen gene family. It is important in the regulation of maternal and fetal metabolis, as well as the growth and development of the fetus. HPL is a secreted by the syncytiotrophoblast during pregnancy. Antibody to HPL reacts with syncytiotrophoblastic cells in choriocarcinoma and intermediate trophoblasts in trophoblastic tumors. It is a useful marker for tumors with trophoblast differentiation.