HER2 / ErbB2 are one of four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases. HER2 is overexpressed in 25–30% of all breast cancers, including primary as well as metastatic breast tumors. HER2 has been widely investigated as a prognostic indicator.
HER2 / ErbB2 are one of four members of the ErbB receptor family of transmembrane receptor-like tyrosine kinases. HER2 is overexpressed in 25–30% of all breast cancers, including primary as well as metastatic breast tumors. HER2 has been widely investigated as a prognostic indicator.