CD163 is an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, thereby protecting tissues from free hemoglobin- mediated oxidative damage. Expression of CD163 is restricted to cells of the monocyte/macrophage lineage. This antibody labels monocytes and macrophages in the spleen and peripheral blood. The CD163 antibody might be used for identifying tumors of monocytic origin.
CD163 is an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, thereby protecting tissues from free hemoglobin- mediated oxidative damage. Expression of CD163 is restricted to cells of the monocyte/macrophage lineage. This antibody labels monocytes and macrophages in the spleen and peripheral blood. The CD163 antibody might be used for identifying tumors of monocytic origin.