SOX2-EP103

Glioma stained with Anti-SOX2

SOX2-EP103

SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. It is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression. 

  • Description
  • Specifications
  • Ordering Information
  • Publications

SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. It is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct3/4 expression. 

  • Source
    Rabbit Monoclonal
  • Clone
    EP103
  • Class
    IVD
  • Isotype
    Rabbit IgG
  • Tested Reactivity
    Human,FFPE
  • Localization
    Nucleus
  • Positive Control
    Oligodendroglioma, Fetal Brain
  • Catalog
    Pack Size
  • PR071-3ml
    3 ml(RTU)
  • PR071-6ml
    6 ml(RTU)
  • CR071-0.1ml
    0.1 ml(Conc.)
  • CR071-0.5ml
    0.5 ml(Conc.)
  • HAR071-3ml
    3 ml(RTU)
  • HAR071-6ml
    6 ml(RTU)
  • CR071 - 1ml
    1ml ( Conc. )

  1. Association of the co-expression of SOX2 and Podoplanin in the progression of oral squamous cell carcinomas - an  immunohistochemical study
    https://www.scielo.br/scielo.php?pid=S1678-77572019000100473&script=sci_arttext
  2. Evaluation of SOX2 and podoplanin expression in oral epithelial dysplasia and its correlation with malignant transformation
    https://onlinelibrary.wiley.com/doi/abs/10.1111/jicd.12450
  3. Cancer stem cell markers, SOX 2 and OCT 4 in ameloblastoma and keratocystic odontogenic tumor: An immunohistochemical study
    https://www.jioh.org/article.asp?issn=0976-7428;year=2017;volume=9;issue=1;spage=28;epage=32;aulast=Bandyopadhyay;type=3