c-Kit/CD117-EP10

Member of the Tyrosine Kinase Receptor (TKRs) and highly homologous to receptor PDF and CSF-1. Activation of c-Kit tyrosine kinase by SCF (Stem Cell factor) leads to autophosphorylation and association of c-Kit with substrate PI3K.  c-Kit/CD117 is a marker for mast cell and gastrointestinal stromal tumor.

• Source
  Rabbit Monoclonal
• Clone
  EP10
• Class
  IVD
• Isotype
  Rabbit IgG
• Tested Reactivity
  Human, FFPE
• Localization
  Membrane, Cytoplasm
• Positive Control
  Gastrointestinal stromal tumor

• Catalog
  Pack Size
• PR033-3ml
  3 ml(RTU)
• PR033-6ml
  6 ml(RTU)
• CR033-0.1ml
  0.1 ml(Conc.)
• CR033-0.5ml
  0.5 ml(Conc.)
• HAR033-3ml
  3 ml(RTU)
• HAR033-6ml
  6 ml(RTU)
• CR033 - 1ml
  1ml ( Conc. )

1. A study on immunohistochemical expression of c-kit in invasive breast carcinoma and its clinicopathological correlation.
   http://repository-tnmgrmu.ac.in/12527/1/200300117lavanya.pdf